PRX editors make every effort to arrive at a clear decision on the disposition of a manuscript within a reasonable time. How long should I wait for a response from the journal? The main editor is usually quite quick (a couple of days or so) because their just gauging scope and relavence. Decisions by editors are routinely made very rapidly after receipt of reports, and Nature offers an advance online publication (AOP) service to an increasing number of manuscripts. [2] In any state, sovereignty is assigned to the person, body, or institution that has the ultimate authority over other people in order to establish a law or change . In replying to the referees comments, authors are advised to use language that would not cause offence when their paper is shown again to the referees, and to bear in mind that if a point was not clear to the referees and/or editors, it is unlikely that it would be clear to the nonspecialist readers of Nature.